Women, 35-45 yrs: overweight with Type 2 Diabetes Research project examining how fat stored in the muscles affects insulin activity. Two days of testing at the Clinical Translational Research Center, Anschutz Medical Campus Exclusions: serious health problems, smoking, taking hormones or medicine to lower glucose (Metformin is okay!) PI: Bryan Bergman, PhD, COMIRB #10-0443, 5/27/2011